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--- ebm:ebm_course [2020/07/28 23:05] – created dhawann
+++ ebm:ebm_course [2020/09/01 00:10] (current) – [Session #3 Lit search review and empircism vs theory vs experts] dhawann
@@ Line 1: / Line 1: @@
-====== Grecia Sanchez ======
+====== EBM Notes ======
 ===== Session #1 Goals/Finding the literature =====
-  * Better understanding on children's upbringings and how that effects adulthood.
+Goals of course: Better understanding on children's upbringings and how that effects adulthood. As well as pharmacology. \\
-  * How to do a evidence based research
+  * went through how to find pubmed through library.uthscsa.edu website
+  * How to do a evidence based research using the PICO methodology
 P - population I - intervention C - control group/comparator O - outcome
-("child abuse" OR "child neglect" OR "adolescent violence") AND (CPS OR adoption) AND (substance use OR alcohol OR methamphetamines OR "externalizing disorder")
+("child abuse" OR "child neglect" OR "adolescent violence") AND (CPS OR adoption) AND (substance use OR alcohol OR methamphetamines OR "externalizing disorder")\\
+in the above example we used PICO methodology\\
+P = "child abuse" OR "child neglect" OR "adolescent violence"
+I = (CPS OR adoption)
+C = no comparator given as there didn't seem to be a clear comparator we could use
+O = (substance use OR alcohol OR methamphetamines OR ...)\\
-  * went through how to find pubmed through library.uthscsa.edy website
+  * how the PICO methodology will fall short if you don't know the right search terms.
   * we discussed my methodology of finding a review to find the right search terms.
+  * Google scholar can be used for finding a review quite effectively.
-===== Session #2 Grecia finds an RCT and we discuss =====
+===== Session #2 Student to find an RCT and we discuss =====
-===== Session #3 Discuss about RCT'S and pharmacology =====
-===== Seminal Child Psych papers???? =====
-  * Look at ACE study
-https://www.scopus.com/record/display.uri?eid=2-s2.0-0032078822&origin=resultslist&sort=cp-f&src=s&st1=%28child+OR+adolescent+OR+teen*+OR+pediatric%29+AND+%28depress*%29&st2=&sid=66a74dbee4899e27389499139fb45342&sot=b&sdt=b&sl=73&s=TITLE-ABS-KEY%28%28child+OR+adolescent+OR+teen*+OR+pediatric%29+AND+%28depress*%29%29&relpos=4&citeCnt=6091&searchTerm=
-  * 1998 study with LARGE number of citations
-  * Look at study of consequences of teen dating violence
-https://www.scopus.com/record/display.uri?eid=2-s2.0-84872875794&origin=resultslist&sort=cp-f&src=s&nlo=&nlr=&nls=&sid=ef67497bcffa52de5f764a08b9f5e122&sot=b&sdt=cl&cluster=scosubjabbr%2c%22MEDI%22%2ct%2bscopubyr%2c%222020%22%2ct%2c%222019%22%2ct%2c%222018%22%2ct%2c%222017%22%2ct%2c%222016%22%2ct%2c%222015%22%2ct%2c%222014%22%2ct%2c%222013%22%2ct%2c%222012%22%2ct%2c%222011%22%2ct%2bscosubtype%2c%22ar%22%2ct&sl=131&s=TITLE-ABS-KEY%28%28child+OR+adolescent+OR+teen*+OR+pediatric%29+%28Psychiatry+OR+Depression+OR+Bipolar+OR+Suicide+OR+adhd+OR+intellectual%29%29&relpos=75&citeCnt=364&searchTerm=
-  * Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample
-https://www.scopus.com/record/display.uri?eid=2-s2.0-56549097085&origin=resultslist&sort=cp-f&src=s&nlo=&nlr=&nls=&sid=92fde1331e353ade516e087731b42500&sot=a&sdt=cl&cluster=scosubtype%2c%22ar%22%2ct%2bscosubjabbr%2c%22MEDI%22%2ct&sl=61&s=TITLE-ABS-KEY%28%28%22conduct+disorder%22+OR+%22oppositional+defiant%22%29%29&relpos=5&citeCnt=1570&searchTerm=
-  * Prevalence, persistence, and sociodemographic correlates of DSM-IV disorders in the National Comorbidity Survey Replication Adolescent Supplement
-https://www.scopus.com/record/display.uri?eid=2-s2.0-84859468680&origin=resultslist&sort=cp-f&src=s&nlo=&nlr=&nls=&sid=2668fdd7e4fc80562d14523f5d124c82&sot=a&sdt=cl&cluster=scosubtype%2c%22ar%22%2ct%2bscosubjabbr%2c%22MEDI%22%2ct%2bscopubyr%2c%222020%22%2ct%2c%222019%22%2ct%2c%222018%22%2ct%2c%222017%22%2ct%2c%222016%22%2ct%2c%222015%22%2ct%2c%222014%22%2ct%2c%222013%22%2ct%2c%222012%22%2ct%2c%222011%22%2ct&sl=61&s=TITLE-ABS-KEY%28%28%22conduct+disorder%22+OR+%22oppositional+defiant%22%29%29&relpos=3&citeCnt=523&searchTerm=
-  * Suicide attempts and nonsuicidal self-injury in the treatment of resistant depression in adolescents: Findings from the TORDIA study
-https://www.scopus.com/record/display.uri?eid=2-s2.0-79960750845&origin=resultslist&sort=cp-f&src=s&nlo=&nlr=&nls=&sid=2668fdd7e4fc80562d14523f5d124c82&sot=a&sdt=cl&cluster=scosubtype%2c%22ar%22%2ct%2bscosubjabbr%2c%22MEDI%22%2ct%2bscopubyr%2c%222020%22%2ct%2c%222019%22%2ct%2c%222018%22%2ct%2c%222017%22%2ct%2c%222016%22%2ct%2c%222015%22%2ct%2c%222014%22%2ct%2c%222013%22%2ct%2c%222012%22%2ct%2c%222011%22%2ct&sl=61&s=TITLE-ABS-KEY%28%28%22conduct+disorder%22+OR+%22oppositional+defiant%22%29%29&relpos=13&citeCnt=251&searchTerm=
-  * Clinicopathological significance of psychotic experiences in non-psychotic young people: Evidence from four population-based studies
-https://www.scopus.com/record/display.uri?eid=2-s2.0-84863567314&origin=resultslist&sort=cp-f&src=s&nlo=&nlr=&nls=&sid=2668fdd7e4fc80562d14523f5d124c82&sot=a&sdt=cl&cluster=scosubtype%2c%22ar%22%2ct%2bscosubjabbr%2c%22MEDI%22%2ct%2bscopubyr%2c%222020%22%2ct%2c%222019%22%2ct%2c%222018%22%2ct%2c%222017%22%2ct%2c%222016%22%2ct%2c%222015%22%2ct%2c%222014%22%2ct%2c%222013%22%2ct%2c%222012%22%2ct%2c%222011%22%2ct&sl=61&s=TITLE-ABS-KEY%28%28%22conduct+disorder%22+OR+%22oppositional+defiant%22%29%29&relpos=12&citeCnt=256&searchTerm=
-  * Mortality in children, adolescents, and adults with attention deficit hyperactivity disorder: A nationwide cohort study
-https://www.scopus.com/record/display.uri?eid=2-s2.0-84930090635&origin=resultslist&sort=cp-f&src=s&nlo=&nlr=&nls=&sid=2668fdd7e4fc80562d14523f5d124c82&sot=a&sdt=cl&cluster=scosubtype%2c%22ar%22%2ct%2bscosubjabbr%2c%22MEDI%22%2ct%2bscopubyr%2c%222020%22%2ct%2c%222019%22%2ct%2c%222018%22%2ct%2c%222017%22%2ct%2c%222016%22%2ct%2c%222015%22%2ct%2c%222014%22%2ct%2c%222013%22%2ct%2c%222012%22%2ct%2c%222011%22%2ct&sl=61&s=TITLE-ABS-KEY%28%28%22conduct+disorder%22+OR+%22oppositional+defiant%22%29%29&relpos=16&citeCnt=233&searchTerm=
-  * Prevalence of psychiatric disorders in preschoolers
+===== Session #3 Lit search review and empircism vs theory vs experts =====
+Two explanatory models for pharmacology:\\
+- Theory
+  - Stahl says
+     - This receptor affects anxiety and this other drug also affects that receptor therefore patients with OCD symptoms or intrusive thoughts in MDD should take this drug.
+  - Freud and his id/ego/superego and ideas like the schizophrenigenic mother.
+  - Galen with his humors.
+- Empirical
+  - We gave this intervention to a population and they responded like this.
-https://www.scopus.com/record/display.uri?eid=2-s2.0-84861333841&origin=resultslist&sort=cp-f&src=s&nlo=&nlr=&nls=&sid=2668fdd7e4fc80562d14523f5d124c82&sot=a&sdt=cl&cluster=scosubtype%2c%22ar%22%2ct%2bscosubjabbr%2c%22MEDI%22%2ct%2bscopubyr%2c%222020%22%2ct%2c%222019%22%2ct%2c%222018%22%2ct%2c%222017%22%2ct%2c%222016%22%2ct%2c%222015%22%2ct%2c%222014%22%2ct%2c%222013%22%2ct%2c%222012%22%2ct%2c%222011%22%2ct&sl=61&s=TITLE-ABS-KEY%28%28%22conduct+disorder%22+OR+%22oppositional+defiant%22%29%29&relpos=15&citeCnt=245&searchTerm=
+[[http://jamaevidence.mhmedical.com/MultimediaPlayer.aspx?MultimediaID=13416590|JAMA Evidence podcast: Gordon Guyatt discussing theory of EBM]] go to 12:20 into the podcast.
+{{ :ebm:ebmvsnonebm.pdf |Short article justifying EBM}}
+===== Session #4 Discuss about RCT'S and pharmacology =====